Product overview
Description Anti-RARG rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human RARG
Reactivity Human
Content 0.3 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol RARG
Full name retinoic acid receptor, gamma
Synonyms RARC; NR1B3
Swissprot P13631
Target Background
This gene encodes a retinoic acid receptor that belongs to the nuclear hormone receptor family. Retinoic acid receptors (RARs) act as ligand-dependent transcriptional regulators. When bound to ligands, RARs activate transcription by binding as heterodimers to the retinoic acid response elements (RARE) found in the promoter regions of the target genes. In their unbound form, RARs repress transcription of their target genes. RARs are involved in various biological processes, including limb bud development, skeletal growth, and matrix homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Applications
Immunohistochemistry
Predicted cell location: Nucleus
Positive control: Human thyroid cancer
Recommended dilution: 20-100
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using ml262110(RARG Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)