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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Synthetic peptide of human RNF217
- 形态:
liquid
- 保存条件:
Store at -20˚C
- 克隆性:
Polyclonal
- 适应物种:
Human;Mouse
- 保质期:
12 months
- 抗原来源:
Rabbit
- 供应商:
南京赛戈巍生物科技有限公司
- 宿主:
Rabbit
- 应用范围:
WB
- 靶点:
Uniprot:Q8TC41
- 抗体英文名:
RNF217 Antibody
- 规格:
50ul/100ul
计算分子量:59 kDa
配方:Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
应用详情:
WB dilution:1:200-1000
图片:

Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: HepG2 cell lysate, Primary antibody:47643(RNF217 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
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文献和实验Nat Commun:结直肠癌致癌突变 RNF43_pG659fs 对 PI3K/mTOR 抑制剂敏感
RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition 的研究论文,揭示了 RNF43_p.G659fs 突变在结直肠癌的致癌机制,并对 PI3K/mTOR 抑制剂敏感。 RNF43 是一种 E3 泛素连接酶,Wnt 信号通路的主要负向调节因子,编码 783aa 的锌指蛋白,2014 年 Giannakis 团队在 Nature
Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
The importance of antibody molecules was first recognized in the 1890s, when it was shown that immunity to tetanus and diphtheria was caused by antibodies against the bacterial exotoxins (1 ). Around the same time, it was shown that antisera
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