Anti-KCNMB3 antibody

Anti-KCNMB3 antibody

Cat. No.     JC261823
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-KCNMB3 rabbit polyclonal antibody
Applications        ELISA, WB, IHC 
Immunogen               Synthetic peptide of human KCNMB3
Reactivity                 Human, Mouse
Content                     0.5 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 KCNMB3
Full name                 potassium large conductance calcium-activated channel, subfamily M beta member 3
Synonyms    HBETA3; KCNMB2; KCNMBL; BKBETA3; SLOBETA3; SLO-BETA-3; K(VCA)BETA-3
Swissprot    Q9NPA1

Target Background
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 22.

Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human brain
Recommended dilution: 25-100    
            
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using ml261823(KCNMB3 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)    
Western blotting
Predicted band size:32 kDa
Positive control:Mouse brain tissue 
Recommended dilution: 500-2000