Anti-SERPINA7 antibody

Anti-SERPINA7 antibody

Cat. No.     JC123329        
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-SERPINA7 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Full length fusion protein
Reactivity                 Human
Content                     0.7 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-SERPINA7 antibody
Target information
Symbol                 SERPINA7
Full name                 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
Synonyms    TBG
Swissprot    P05543

Target Background
There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.

Anti-SERPINA7 antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human thyroid cancer
Recommended dilution: 25-100    Predicted cell location: Cytoplasm
Positive control: Human prostate cancer
Recommended dilution: 25-100