Product overview
Description Anti-EXO5 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human EXO5
Reactivity Human, Mouse
Content 0.3 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol EXO5
Full name exonuclease 5
Synonyms DEM1; Exo V; hExo5; C1orf176
Swissprot Q9H790
Target Background
The protein encoded by this gene is a single-stranded DNA (ssDNA)-specific exonuclease that can slide along the DNA before cutting it. However, human replication protein A binds ssDNA and restricts sliding of the encoded protein, providing a 5'-directionality to the enzyme. This protein localizes to nuclear repair loci after DNA damage.