Product overview
Description Anti-EVC2 rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Synthetic peptide of human EVC2
Reactivity Human, Mouse
Content 2.22 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol EVC2
Full name EvC ciliary complex subunit 2
Synonyms LBN; WAD
Swissprot Q86UK5
Target Background
This gene encodes a protein that functions in bone formation and skeletal development. Mutations in this gene, as well as in a neighboring gene that lies in a head-to-head configuration, cause Ellis-van Creveld syndrome, an autosomal recessive skeletal dysplasia that is also known as chondroectodermal dysplasia. Mutations in this gene also cause acrofacial dysostosis Weyers type, also referred to as Curry-Hall syndrome, a disease that combines limb and facial abnormalities. Alternative splicing results in multiple transcript variants.
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm and Cell membrane
Positive control: Human cervical cancer
Recommended dilution: 50-300 Predicted cell location: Cytoplasm and Cell membrane
Positive control: Human colorectal cancer
Recommended dilution: 50-300
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using ml261664(EVC2 Antibody) at dilution 1/75, on the right is treated with synthetic peptide. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using ml261664(EVC2 Antibody) at dilution 1/75, on the right is treated with synthetic peptide. (Original magnification: ×200)
Western blotting
Predicted band size:148 kDa
Positive control:Raji and A375 cell lysates
Recommended dilution: 500-2000