Anti-CD5L antibody

Anti-CD5L antibody

Cat. No.     JC261540
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-CD5L rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human CD5L
Reactivity                 Human, Mouse
Content                     0.4 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 CD5L
Full name                 CD5 molecule-like
Synonyms    AIM; API6; PRO229; Spalpha; SP-ALPHA
Swissprot    O43866

Target Background
CD5L (CD5 molecule-like), also known as API6, PRO229, Spalpha or SP-ALPHA, is a 347 amino acid secreted protein that belongs to the scavenger receptor cysteine-rich (SRCR) family of leukocyte regulating proteins. Expressed in bone marrow, spleen, thymus, lymph node and fetal liver, CD5L is thought to be involved in regulating the immune system via binding to peripheral monocytes and mediating their activation and overall survival. CD5L has three cysteine-rich domains and, in addition to its role in the immune system, may function to inhibit apoptosis and promote macrophage survival.

Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human Lymphoma
Recommended dilution: 50-200    Predicted cell location: Cytoplasm
Positive control: Human liver cancer
Recommended dilution: 50-200
            
The image on the left is immunohistochemistry of paraffin-embedded Human Lymphoma tissue using ml261540(CD5L Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)    The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using ml261540(CD5L Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)

ELISA
Recommended dilution: 1000-5000