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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
上海机纯实业有限公司
- 库存:
大量
- 克隆性:
多克隆
- 保质期:
12个月
- 抗体英文名:
Anti-NEDD4L antibody
- 宿主:
Rabbit
- 适应物种:
人/动物/植物
- 应用范围:
ELISA, WB
- 浓度:
0.4 mg/ml
- 保存条件:
-20°C
- 规格:
25 μl/100 μl/200 μl
Cat. No. JC122760
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-NEDD4L rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human NEDD4L
Reactivity Human, Mouse
Content 0.4 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Anti-NEDD4L antibody
Target information
Symbol NEDD4L
Full name neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
Synonyms RSP5; NEDD4-2; NEDD4.2; hNEDD4-2
Swissprot Q96PU5
Target Background
This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension.
Anti-NEDD4L antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human prostate cancer
Recommended dilution: 100-300 Predicted cell location: Cytoplasm
Positive control: Human liver cancer
Recommended dilution: 100-300
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