FITC标记的铁调节蛋白/铁调素抗体

FITC标记的铁调节蛋白/铁调素抗体

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  • ¥2980
  • LMAI Bio
  • LM-8870R-FITC
  • 中国/美国/欧洲
  • 2025年06月23日
  • ICC=1:50-200 IF=1:50-200
  • Mouse, Rat,
  • Mouse, Rat,
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    • 详细信息
    • 技术资料
    • 供应商

      上海联迈生物工程有限公司

    • 库存

      大量

    • 靶点

      详见说明书

    • 级别

      1

    • 目录编号

      LM-8870R-FITC

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      1年

    • 抗体英文名

      Anti-Hepcidin-25/FITC

    • 抗体名

      Anti-Hepcidin-25/FITC

    • 标记物

      FITC标记

    • 宿主

      Mouse, Rat,

    • 适应物种

      Mouse, Rat,

    • 免疫原

      详见说明书

    • 亚型

      IGg

    • 形态

      粉末、液体、冻干粉

    • 应用范围

      ICC=1:50-200 IF=1:50-200

    • 浓度

      1mg/ml

    • 保存条件

      -20 °C

    • 规格

      100ul

    FITC标记的铁调节蛋白/铁调素抗体
    英文名称 Anti-Hepcidin-25/FITC
    中文名称 FITC标记的铁调节蛋白/铁调素抗体
    别    名 Hamp; HEPC; HEPC_RAT; HEPC_MOUSE; Hepc20; Hepc25; HEPCIDIN; Hepcidin; Hepcidin 20; Hepcidin 25; Hepcidin antimicrobial peptide; Hepcidin-20; Hepcidin25; HFE2; HFE2B; LEAP 1; LEAP-1; LEAP1; Liver expressed antimicrobial peptide; Liver-expressed antimicrobial peptide 1; PLTR; Putative liver tumor regressor.  
    规格价格 100ul/2980元 购买        大包装/询价
    说 明 书 100ul  
    研究领域 肿瘤  心血管  细胞生物  信号转导  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Mouse, Rat, 
    产品应用 ICC=1:50-200 IF=1:50-200  
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 2kDa
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from rat Hepcidin
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    产品介绍 background:
    The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. [provided by RefSeq, Jul 2008].

    Subcellular Location:
    Secreted.

    Tissue Specificity:
    Highest expression in liver and to a lesser extent in heart and brain. Low levels in lung, tonsils, salivary gland, trachea, prostate gland, adrenal gland and thyroid gland. Secreted into the urine.

    DISEASE:
    Defects in HAMP are the cause of hemochromatosis type 2B (HFE2B) [MIM:613313]; also known as juvenile hemochromatosis (JH). HFE2B is a disorder of iron metabolism with excess deposition of iron in the tissues, bronze skin pigmentation, hepatic cirrhosis, arthropathy and diabetes. The most common symptoms of hemochromatosis type 2 at presentation are hypogonadism and cardiomyopathy.

    Similarity:
    Belongs to the hepcidin family.

    Database links:

    Entrez Gene: 57817 Human

    Entrez Gene: 84506 Mouse

    Entrez Gene: 84604 Rat

    Omim: 606464 Human

    SwissProt: P81172 Human

    SwissProt: Q9EQ21 Mouse

    SwissProt: Q99MH3 Rat

    Unigene: 8821 Human

    Unigene: 7865 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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