Anti-CEL antibody

Anti-CEL antibody

Cat. No.     JC261482
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-CEL rabbit polyclonal antibody
Applications        ELISA, WB, IHC 
Immunogen               Synthetic peptide of human CEL
Reactivity                 Human
Content                     0.5 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 CEL
Full name                 carboxyl ester lipase
Synonyms    BAL; FAP; BSDL; BSSL; CELL; FAPP; LIPA; CEase; MODY8
Swissprot    P19835

Target Background
The protein encoded by this gene is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted.

Applications
Immunohistochemistry
Predicted cell location: Nucleus
Positive control: Human colon cancer
Recommended dilution: 50-200    Predicted cell location: Nucleus
Positive control: Human brain
Recommended dilution: 50-200
            
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using ml261482(CEL Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)    The image on the left is immunohistochemistry of paraffin-embedded Human brain  tissue using ml261482(CEL Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
Western blotting
Predicted band size:79 kDa
Positive control:Hela and hepG2 cells 
Recommended dilution: 200-1000