Product overview
Description Anti-RGS5 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human RGS5
Reactivity Human, Mouse, Rat
Content 0.4 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol RGS5
Full name regulator of G-protein signaling 5
Synonyms MST092; MST106; MST129; MSTP032; MSTP092; MSTP106; MSTP129
Swissprot O15539
Target Background
This gene encodes a member of the regulators of G protein signaling (RGS) family. The RGS proteins are signal transduction molecules which are involved in the regulation of heterotrimeric G proteins by acting as GTPase activators. This gene is a hypoxia-inducible factor-1 dependent, hypoxia-induced gene which is involved in the induction of endothelial apoptosis. This gene is also one of three genes on chromosome 1q contributing to elevated blood pressure. Alternatively spliced transcript variants have been identified.