Anti-HK2 antibody

Anti-HK2 antibody

Cat. No.      JC121853        
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-HK2 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Fusion protein of human HK2
Reactivity                 Human, Mouse, Rat
Content                     0.4 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-HK2 antibody
Target information
Symbol                 HK2
Full name                 hexokinase 2
Synonyms    HKII; HXK2
Swissprot    P52789

Target Background
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.

Anti-HK2 antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human brain
Recommended dilution: 50-200    Predicted cell location: Cytoplasm
Positive control: Human thyroid cancer
Recommended dilution: 50-200