Anti-NOTCH1 antibody

Anti-NOTCH1 antibody

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  • 询价
  • gelatins
  • JLC261041
  • 上海
  • 2025年07月13日
  • Rabbit
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    • 详细信息
    • 技术资料
    • 供应商

      江西江蓝纯生物试剂有限公司

    • 库存

      大量

    • 克隆性

      多克隆

    • 保质期

      1年

    • 抗体英文名

      Anti-NOTCH1 antibody

    • 宿主

      Rabbit

    • 浓度

      0.3 mg/ml

    • 保存条件

      -20°C

    • 规格

      25 μl/100 μl/200 μl

    Anti-NOTCH1 antibody

    Cat. No.    JLC261041        
    Package    25 μl/100 μl/200 μl
    Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

    Product overview
    Description                   Anti-NOTCH1 rabbit polyclonal antibody
    Applications        ELISA, WB 
    Immunogen               Synthetic peptide of human NOTCH1
    Reactivity                 Human, Rat
    Content                     0.3 mg/ml
    Host species               Rabbit
    Ig class                  Immunogen-specific rabbit IgG
    Purification                 Antigen affinity purification

    Target information
    Symbol                 NOTCH1
    Full name                 Notch 1
    Synonyms    hN1; TAN1
    Swissprot    P46531

    Target Background
    This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play multiple roles during development.
    Anti-NOTCH1 antibody
    Applications
    Western blotting
    Predicted band size:273 kDa
    Positive control:HT-29 cells 
    Recommended dilution: 200-1000

    Gel: 8%SDS-PAGE
    Lysate: 60 μg
    Lane: HT29 cells
    Primary antibody: ml261041(NOTCH1 Antibody) at dilution 1/300
    Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution
    Exposure time: 1 minute
                            
    ELISA
    Recommended dilution:1000-2000

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