Anti-UNCX antibody

Anti-UNCX antibody

Cat. No.     JLC163238
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-UNCX rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human UNCX
Reactivity                 Human, Mouse
Content                     0.4 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification



Target information
Symbol                 UNCX
Full name                 UNC homeobox
Synonyms    UNCX4.1
Swissprot    A6NJT0

Target Background
UNCX (UNC homeobox), also known as UNCX4.1, is a 531 amino acid nuclear transcription factor involved in neurogenesis and somitogenesis. Containing one homeobox DNA-binding domain, UNCX belongs to the paired homeobox family and UNC4 subfamily. UNCX assists in the formation of connections between hypothalamic neurons and the pituitary, which is necessary for central neurons to deliver hormones into peripheral blood. UNCX also plays a role in maintaining differentiation of the axial skeleton and acts upstream of Pax-9. The gene encoding UNCX maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.