FITC标记的ATP6V0D2蛋白抗体

FITC标记的ATP6V0D2蛋白抗体

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  • ¥2980
  • LMAI Bio
  • LM-12548R-FITC
  • 中国/美国/欧洲
  • 2025年07月03日
  • ICC=1:50-200 IF=1:50-200
  • Human, Mouse, Rat, Dog, Pig, Sheep,
  • Human, Mouse, Rat, Dog, Pig, Sheep,
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    • 详细信息
    • 技术资料
    • 供应商

      上海联迈生物工程有限公司

    • 库存

      大量

    • 靶点

      详见说明书

    • 级别

      1

    • 目录编号

      LM-12548R-FITC

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      1年

    • 抗体英文名

      Anti-ATP6V0D2/FITC

    • 抗体名

      Anti-ATP6V0D2/FITC

    • 标记物

      FITC标记

    • 宿主

      Human, Mouse, Rat, Dog, Pig, Sheep,

    • 适应物种

      Human, Mouse, Rat, Dog, Pig, Sheep,

    • 免疫原

      详见说明书

    • 亚型

      IGg

    • 形态

      粉末、液体、冻干粉

    • 应用范围

      ICC=1:50-200 IF=1:50-200

    • 浓度

      1mg/ml

    • 保存条件

      -20 °C

    • 规格

      100ul

    FITC标记的ATP6V0D2蛋白抗体
    英文名称 Anti-ATP6V0D2/FITC
    中文名称 FITC标记的ATP6V0D2蛋白抗体
    别    名 V-ATPase D2; ATP6D2; ATPase H+ transporting lysosomal 38kDa V0 subunit D; ATPase H+ transporting lysosomal 38kDa V0 subunit D isoform 2; ATPase H+ transporting lysosomal 38kDa V0 subunit D2; FLJ38708; V ATPase subunit d 2; Vacuolar ATP synthase subunit d 2; Vacuolar proton pump subunit d 2; VMA 6; VMA6; VA0D2_HUMAN.  
    规格价格 100ul/2980元 购买        大包装/询价
    说 明 书 100ul  
    研究领域 肿瘤  细胞生物  信号转导  新陈代谢  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, Dog, Pig, Sheep, 
    产品应用 ICC=1:50-200 IF=1:50-200  
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 40kDa
    细胞定位 细胞膜 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human ATP6V0D2/V-ATPase D2
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    产品介绍 background:
    Vacuolar-type H+-ATPase (V-ATPase) is a multisubunit enzyme responsible for acidification of eukaryotic intracellular organelles. V-ATPases pump protons against an electrochemical gradient, while F-ATPases reverse the process, thereby synthesizing ATP. A peripheral V1 domain, which is responsible for ATP hydrolysis, and a integral V0 domain, which is responsible for proton translocation, compose V-ATPase. Nine subunits (A–H) make up the V1 domain and five subunits (a, d, c, c' and c") make up the V0 domain. Like F-ATPase, V-ATPase most likely operates through a rotary mechanism. V-ATPase D2 is a 350 amino acid protein that is expressed in kidney, lung and osteoclast. V-ATPase D2 has been implicated as a regulator of urine acidification, osteoclast fusion and bone formation. Furthermore, V-ATPase D2 has been identified as a dendritic cell marker.

    Function:
    Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity). 

    Subunit:
    V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'' and d). 

    Subcellular Location:
    Apical plasma membrane.

    Tissue Specificity:
    Kidney, osteoclast and lung. 

    Similarity:
    Belongs to the V-ATPase V0D/AC39 subunit family. 

    Database links:

    Entrez Gene: 245972 Human

    Entrez Gene: 242341 Mouse

    Entrez Gene: 297932 Rat

    SwissProt: Q8N8Y2 Human

    SwissProt: Q80SY3 Mouse

    SwissProt: Q5FVL0 Rat

    Unigene: 436360 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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