Anti-TSC2 antibody

Anti-TSC2 antibody

Cat. No.     JLC162433
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-TSC2 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human TSC2
Reactivity                 Human, Mouse, Rat
Content                     0.3 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification



Target information
Symbol                 TSC2
Full name                 tuberous sclerosis 2
Synonyms    LAM; TSC4; PPP1R160
Swissprot    P49815

Target Background
Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.