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- 详细信息
- 技术资料
- 供应商:
江西江蓝纯生物试剂有限公司
- 库存:
大量
- 克隆性:
多克隆
- 保质期:
1年
- 抗体英文名:
Anti-pan-AKT antibody
- 宿主:
Rabbit
- 浓度:
0.72 mg/ml
- 保存条件:
-20°C
- 规格:
25 μl/100 μl/200 μl
Anti-pan-AKT antibody
Cat. No. JLC260001
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-pan-AKT rabbit polyclonal antibody
Applications ELISA, WB
Immunogen Synthetic peptide of human pan-AKT
Reactivity Human, Mouse, Rat
Content 0.72 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol pan-AKT
Full name RAC-alpha serine/threonine-protein kinase
Synonyms PKB, RAC, PRKBA, PKB-ALPHA, RAC-ALPHA
Swissprot P31749
Target Background
The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene.

Applications
Western blotting
Predicted band size:56 kDa
Positive control:NIH/3T3 cells
Recommended dilution: 500-1000
Gel: 10%SDS-PAGE
Lysate: 30 μg
Lane: NIH/3T3 cells
Primary antibody: ml260001(pan-AKT Antibody) at dilution 1/500
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution
Exposure time: 10 minutes
ELISA
Recommended dilution:2000-10000
Cat. No. JLC260001
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-pan-AKT rabbit polyclonal antibody
Applications ELISA, WB
Immunogen Synthetic peptide of human pan-AKT
Reactivity Human, Mouse, Rat
Content 0.72 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol pan-AKT
Full name RAC-alpha serine/threonine-protein kinase
Synonyms PKB, RAC, PRKBA, PKB-ALPHA, RAC-ALPHA
Swissprot P31749
Target Background
The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene.

Applications
Western blotting
Predicted band size:56 kDa
Positive control:NIH/3T3 cells
Recommended dilution: 500-1000
Gel: 10%SDS-PAGE
Lysate: 30 μg
Lane: NIH/3T3 cells
Primary antibody: ml260001(pan-AKT Antibody) at dilution 1/500
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution
Exposure time: 10 minutes
ELISA
Recommended dilution:2000-10000
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Anti-pan-AKT antibody
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