Product overview
Description Anti-DEFB104A rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human DEFB104A
Reactivity Human
Content 0.7 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol DEFB104A
Full name defensin beta 104A
Synonyms BD-4; DEFB4; hBD-4; DEFB-4; DEFB104
Swissprot Q8WTQ1
Target Background
Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 104, DEFB104A and DEFB104B, in head-to-head orientation. This gene, DEFB104A, represents the more centromeric copy.