- 询价
- gelatins
- JLC225694
- 上海
- 2025年07月15日
- Rabbit
9 年钻石会员
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 供应商：
江西江蓝纯生物试剂有限公司
- 库存：
大量
- 克隆性：
多克隆
- 保质期：
1年
- 抗体英文名：
Anti-MLKL antibody
- 宿主：
Rabbit
- 浓度：
1.5 mg/ml
- 保存条件：
-20°C
- 规格：
25 μl/100 μl/200 μl
Anti-MLKL antibody
Cat. No. JLC225694
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-MLKL rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human MLKL
Reactivity Human
Content 1.5 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol MLKL
Full name mixed lineage kinase domain like pseudokinase
Synonyms hMLKL
Swissprot Q8NB16
Target Background
This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to be inactive because it lacks several residues required for activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (RIP3), which is a key signaling molecule in necroptosis pathway. Inhibitor studies and knockdown of this gene inhibited TNF-induced necrosis. High levels of this protein and RIP3 are associated with inflammatory bowel disease in children. Alternatively spliced transcript variants have been described for this gene.
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human liver cancer
Recommended dilution: 50-300 Predicted cell location: Cytoplasm
Positive control: Human tonsil
Recommended dilution: 50-300
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using ml225694(MLKL Antibody) at dilution 1/85, on the right is treated with fusion protein. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using ml225694(MLKL Antibody) at dilution 1/85, on the right is treated with fusion protein. (Original magnification: ×200)
ELISA
Recommended dilution: 5000-10000
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
Anti-MLKL antibody
询价
