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- 详细信息
- 技术资料
- 供应商:
江西江蓝纯生物试剂有限公司
- 库存:
大量
- 克隆性:
多克隆
- 保质期:
1年
- 抗体英文名:
Anti-MPZL1 antibody
- 宿主:
Rabbit
- 浓度:
0.96 mg/ml
- 保存条件:
-20°C
- 规格:
25 μl/100 μl/200 μl

Anti-MPZL1 antibody
Cat. No. JLC225582
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-MPZL1 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human MPZL1
Reactivity Human, Mouse, Rat
Content 0.96 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol MPZL1
Full name myelin protein zero like 1
Synonyms PZR; PZRa; PZRb; PZR1b; MPZL1b
Swissprot O95297
Target Background
Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human tonsil
Recommended dilution: 20-100 Predicted cell location: Cytoplasm
Positive control: Human brain
Recommended dilution: 20-100
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using ml225582(MPZL1 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using ml225582(MPZL1 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
ELISA
Recommended dilution: 5000-10000
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Anti-MPZL1 antibody
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