FITC标记的载脂蛋白D抗体

FITC标记的载脂蛋白D抗体

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  • ¥2980
  • LMAI Bio
  • LM-1254R-FITC
  • 中国/美国/欧洲
  • 2025年07月12日
  • IF=1:50-200
  • Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,
  • Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,
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    • 详细信息
    • 技术资料
    • 供应商

      上海联迈生物工程有限公司

    • 库存

      大量

    • 靶点

      详见说明书

    • 级别

      1

    • 目录编号

      LM-1254R-FITC

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      1年

    • 抗体英文名

      Anti-Apolipoprotein D/FITC

    • 抗体名

      Anti-Apolipoprotein D/FITC

    • 标记物

      FITC标记

    • 宿主

      Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,

    • 适应物种

      Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,

    • 免疫原

      详见说明书

    • 亚型

      IGg

    • 形态

      粉末、液体、冻干粉

    • 应用范围

      IF=1:50-200

    • 浓度

      1mg/ml

    • 保存条件

      -20 °C

    • 规格

      100ul

    FITC标记的载脂蛋白D抗体
    英文名称 Anti-Apolipoprotein D/FITC
    中文名称 FITC标记的载脂蛋白D抗体
    别    名 Apolipoprotein D; APOD; APO D; APOD protein; APOD_HUMAN; Apolipoprotein D; Apo-D; ApoD.  
    规格价格 100ul/2980元 购买        大包装/询价
    说 明 书 100ul  
    研究领域 肿瘤  心血管  细胞生物  免疫学  神经生物学  Alzheimer's  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, 
    产品应用 IF=1:50-200  
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 19kDa
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human APOD
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    产品介绍 background:
    Apolipoprotein D (APO D), a glycoprotein involved in the human plasma lipid transport system. It is a progesterone binding glycoprotein of 24,000 dalton monomer molecular size, is a constituent of high density lipoprotein in plasma. The function of apolipoprotein D in the metabolism of plasma lipoproteins is unclear but the observation that this protein forms complexes with lecithin: cholesterol acyltransferase has led to the suggestion that apolipoprotein D may be involved in cholesterol esterification and transport of substrates and products of the reaction. Apolipoprotein D is expressed in a range of normal tissues including axillary apocrine glands, adrenal cortex and corpus luteum. Peripheral nerves, pituitary, testis, cerebellum and renal tubes are also positive. APO D was first isolated in large quantity as GCDFP 24, the major protein component of most human breast cyst fluids. In recent studies, Apo D immunoreactivity has been shown to be an early indicator of prostate cancer and advanced primary prostate tumors.

    Function:
    APOD occurs in the macromolecular complex with lecithin-cholesterol acyltransferase. It is probably involved in the transport and binding of bilin. Appears to be able to transport a variety of ligands in a number of different contexts.

    Subunit:
    Homodimer. In plasma, also exists as a disulfide-linked heterodimer with APOA2.

    Subcellular Location:
    Secreted.

    Tissue Specificity:
    Expressed in liver, intestine, pancreas, kidney, placenta, adrenal, spleen, fetal brain tissue and tears.

    Post-translational modifications:
    N-glycosylatd. N-glycan heterogeneity at Asn-65: Hex5HexNAc4 (major) and Hex6HexNAc5 (minor); at Asn-98: Hex5HexNAc4 (minor), dHex1Hex5HexNAc4 (major), dHex1Hex6HexNAc5 (minor) and dHex1Hex7HexNAc6 (minor).

    Similarity:
    Belongs to the calycin superfamily. Lipocalin family.

    Database links:

    Entrez Gene: 347 Human

    Omim: 107740 Human

    SwissProt: P05090 Human

    Unigene: 522555 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

    载脂蛋白D(apolipoprotein D,apoD)是一个糖蛋白,它最初是在人血浆的高密度脂蛋白中被分离出来的。apoD在结构上与其他类型的载脂蛋白存在很大的差异,被归入脂肪促成素家族。apoD可以与胆固醇、胆红素等多种疏水性小分子结合。
    apoD在多种脊索动物的各类组织中广泛表达, 在脊椎动物中重要的生理功能。最近的研究表明,apoD可以作为多种癌症及神经系统疾病的早期诊断标记, apoD是一个多配体、多功能的蛋白质.

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