Product overview Description Anti-CIAO1 rabbit polyclonal antibody Applications ELISA, IHC Immunogen Fusion protein of human CIAO1 Reactivity Human, Mouse, Rat Content 0.4 mg/ml Host species Rabbit Ig class Immunogen-specific rabbit IgG Purification Antigen affinity purification
Target information Symbol CIAO1 Full name cytosolic iron-sulfur assembly component 1 Synonyms CIA1; WDR39 Swissprot O76071
Target Background Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation.
Applications Immunohistochemistry Predicted cell location: Cytoplasm Positive control: Human brain Recommended dilution: 20-100 Predicted cell location: Cytoplasm Positive control: Human liver cancer Recommended dilution: 20-100
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using ml224562(CIAO1 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using ml224562(CIAO1 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)