- 询价
- gelatins
- JLC224263
- 上海
- 2025年07月12日
- Rabbit
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
江西江蓝纯生物试剂有限公司
- 库存：
大量
- 克隆性：
多克隆
- 保质期：
1年
- 抗体英文名：
Anti-BLNK antibody
- 宿主：
Rabbit
- 浓度：
0.6 mg/ml
- 保存条件：
-20°C
- 规格：
25 μl/100 μl/200 μl
Anti-BLNK antibody
Cat. No. JLC224263
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-BLNK rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human BLNK
Reactivity Human, Mouse, Rat
Content 0.6 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol BLNK
Full name B-cell linker
Synonyms bca; AGM4; BASH; LY57; SLP65; BLNK-S; SLP-65
Swissprot Q8WV28
Target Background
This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene.
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm or Cell membrane
Positive control: Human thyroid cancer
Recommended dilution: 40-200 Predicted cell location: Cytoplasm or Cell membrane
Positive control: Human gastric cancer
Recommended dilution: 40-200
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using ml224263(BLNK Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using ml224263(BLNK Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
ELISA
Recommended dilution: 5000-10000
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