- ¥2980
- LMAI Bio
- LM-0084R-FITC
- 中国/美国/欧洲
- 2025年07月15日
- IF=1:50-200
- Human, Mouse, Rat, Dog, Rabbit,
- Human, Mouse, Rat, Dog, Rabbit,
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- 详细信息
- 技术资料
- 供应商：
上海联迈生物工程有限公司
- 库存：
大量
- 靶点：
详见说明书
- 级别：
1
- 目录编号：
LM-0084R-FITC
- 克隆性：
多克隆
- 抗原来源：
Rabbit
- 保质期：
1年
- 抗体英文名：
Anti-Caspase-6 subunit p18/FITC
- 抗体名：
Anti-Caspase-6 subunit p18/FITC
- 标记物：
FITC标记
- 宿主：
Human, Mouse, Rat, Dog, Rabbit,
- 适应物种：
Human, Mouse, Rat, Dog, Rabbit,
- 免疫原：
详见说明书
- 亚型：
IGg
- 形态：
粉末、液体、冻干粉
- 应用范围：
IF=1:50-200
- 浓度：
1mg/ml
- 保存条件：
-20 °C
- 规格：
100ul
FITC标记的半胱胺酸蛋白酶蛋白-6抗体
| 英文名称 | Anti-Caspase-6 subunit p18/FITC |
| 中文名称 | FITC标记的半胱胺酸蛋白酶蛋白-6抗体 |
| 别 名 | Caspase-6; Caspase-6 p18; cleaved Caspase-6 p18; Apoptosis Related Cysteine Protease; Apoptotic cysteine protease MCH2; Apoptotic protease MCH 2; Apoptotic protease MCH2; Casp 6; Casp6; Caspase 6 apoptosis related cysteine protease; Caspase 6 precursor; Caspase6; Human cysteine protease Mch2 isoform alpha; Mch 2; Mch2; CASP6_HUMAN; caspase-6 isoform alpha precursor. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 神经生物学 信号转导 细胞凋亡 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Rabbit, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 18/33kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Caspase-6 subunit p18 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms. [provided by RefSeq, Jul 2008] Function: Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death. Subunit: Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 18 kDa (p18) and a 11 kDa (p11) subunit. Interacts with BIRC6/bruce. Subcellular Location: Cytoplasm. Post-translational modifications: Cleavages by caspase-3, caspase-8 or -10 generate the two active subunits. Similarity: Belongs to the peptidase C14A family. Database links: Entrez Gene: 839 Human Entrez Gene: 12368 Mouse Entrez Gene: 83584 Rat Omim: 601532 Human SwissProt: P55212 Human SwissProt: O08738 Mouse SwissProt: O35397 Rat Unigene: 654616 Human Unigene: 281379 Mouse Unigene: 88160 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Caspase-6 与Caspase-3有38%的同源性，属胱氨酸-天冬氨酸蛋白酶家族。在凋亡执行阶段起中心作用，可被Caspase-7、-8、-10剪切。它是唯一一个可以剪切核纤层蛋白的Caspase。 |
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FITC标记的半胱胺酸蛋白酶蛋白-6抗体
¥2980
