FITC标记的白介素2受体a链/IL-2RA抗体

FITC标记的白介素2受体a链/IL-2RA抗体

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  • ¥2980
  • LMAI Bio
  • LM-0577R-FITC
  • 中国/美国/欧洲
  • 2025年07月15日
  • Flow-Cyt=1ug/Test
  • Human, Mouse, Rat,
  • Human, Mouse, Rat,
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    • 详细信息
    • 技术资料
    • 供应商

      上海联迈生物工程有限公司

    • 库存

      大量

    • 靶点

      详见说明书

    • 级别

      1

    • 目录编号

      LM-0577R-FITC

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      1年

    • 抗体英文名

      Anti-IL2RA/CD25/FITC

    • 抗体名

      Anti-IL2RA/CD25/FITC

    • 标记物

      FITC标记

    • 宿主

      Human, Mouse, Rat,

    • 适应物种

      Human, Mouse, Rat,

    • 免疫原

      详见说明书

    • 亚型

      IGg

    • 形态

      粉末、液体、冻干粉

    • 应用范围

      Flow-Cyt=1ug/Test

    • 浓度

      1mg/ml

    • 保存条件

      -20 °C

    • 规格

      100ul  

    FITC标记的白介素2受体a链/IL-2RA抗体
    英文名称 Anti-IL2RA/CD25/FITC
    中文名称 FITC标记的白介素2受体a链/IL-2RA抗体
    别    名 Interleukin 2 receptor alpha chain; CD 25; CD25; CD25 antigen; IDDM10; IL 2 RA; IL 2 receptor alpha subunit; IL2 RA; IL-2RA; IL2R; IL2RA; IL2RAC; Interleukin 2 Receptor Alpha; Interleukin 2 receptor alpha chain; Interleukin 2 receptor; Ly43; p55; T Cell Growth Factor Receptor; TAC Antigen; TCGFR; IL2RA_MOUSE.  
    规格价格 100ul/2980元 购买        大包装/询价
    说 明 书 100ul  
    研究领域 肿瘤  免疫学  细胞膜受体  淋巴细胞  t-淋巴细胞  b-淋巴细胞  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, 
    产品应用 Flow-Cyt=1ug/Test  
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 28kDa
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from mouse CD25
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    产品介绍 background:
    The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteoly. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009].

    Function:
    Receptor for interleukin-2.

    Subunit:
    Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.

    Subcellular Location:
    Membrane; Single-pass type I membrane protein.

    Similarity:
    Contains 2 Sushi (CCP/SCR) domains.

    Database links:

    Entrez Gene: 3559 Human

    Entrez Gene: 16184 Mouse

    SwissProt: P01589 Human

    SwissProt: P01590 Mouse

    Unigene: 231367 Human

    Unigene: 915 Mouse

    Omim: 147730 Human

     



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

    CD25抗原是分子量为55KD的单链糖蛋白,故又称白介素2受体。主要用于与淋巴样肿瘤、自身免疫性疾病及同种异体移植排斥反应等疾病的研究。CD25是白介素受体的α亚单位,主要表达于活化的T细胞,在活化的B细胞、NK细胞和巨噬细胞也有一定量的表达。该抗体主要用于标记活化的淋巴细胞。
    产品图片 FITC标记的白介素2受体a链/IL-2RA抗体
    Blank control: Mouse spleen. 
    Primary Antibody (green line): Rabbit Anti-CD25 antibody (bs-0577R-FITC) 
    Dilution: 1μg /10^6 cells; 
    Isotype Control Antibody (orange line): Rabbit IgG .
    Protocol
    The cells were incubated in 5%BSA to block non-specific protein-protein interactions for 30 min at at room temperature .Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature. Acquisition of 20,000 events was performed.

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