FITC标记的单羧酸转运蛋白-1抗体

FITC标记的单羧酸转运蛋白-1抗体

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  • ¥2980
  • LMAI Bio
  • LM-1569R-FITC
  • 中国/美国/欧洲
  • 2025年07月14日
  • Flow-Cyt=1:50-200 IF=1:50-200
  • Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep,
  • Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep,
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    • 详细信息
    • 技术资料
    • 供应商

      上海联迈生物工程有限公司

    • 库存

      大量

    • 靶点

      详见说明书

    • 级别

      1

    • 目录编号

      LM-1569R-FITC

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      1年

    • 抗体英文名

      Anti-MCT1/Malignant T cell amplified sequence 1/FITC

    • 抗体名

      Anti-MCT1/Malignant T cell amplified sequence 1/FITC

    • 标记物

      FITC标记

    • 宿主

      Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep,

    • 适应物种

      Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep,

    • 免疫原

      详见说明书

    • 亚型

      IGg

    • 形态

      粉末、液体、冻干粉

    • 应用范围

      Flow-Cyt=1:50-200 IF=1:50-200

    • 浓度

      1mg/ml

    • 保存条件

      -20 °C

    • 规格

      100ul

    FITC标记的单羧酸转运蛋白-1抗体
    英文名称 Anti-MCT1/Malignant T cell amplified sequence 1/FITC
    中文名称 FITC标记的单羧酸转运蛋白-1抗体
    别    名 monocarboxylate transporter 1; Malignant T cell amplified sequence 1; MCT 1; MCT1; MCTS 1; MCTS1; Oncogene MCT 1; Oncogene MCT1; SLC16A1; FLJ36745; HHF7; MCT; MGC44475; monocarboxylate transporter; Monocarboxylate transporter isoform 1; Monocarboxylic acid transporter 1; SLC16A1; SLC16A1 protein; Solute carrier family 16 (monocarboxylic acid transporters) member 1; Solute carrier family 16 member 1 (monocarboxylic acid transporter 1); Solute carrier family 16 member 1; MOT1_HUMAN.  
    规格价格 100ul/2980元 购买        大包装/询价
    说 明 书 100ul  
    研究领域 免疫学  转运蛋白  交换蛋白  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep, 
    产品应用 Flow-Cyt=1:50-200 IF=1:50-200  
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 55kDa
    细胞定位 细胞膜 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human MCT1
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    产品介绍 background:
    The protein encoded by this gene is a proton-linked monocarboxylate transporter that catalyzes the movement of many monocarboxylates, such as lactate and pyruvate, across the plasma membrane. Mutations in this gene are associated with erythrocyte lactate transporter defect. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2009]

    Function:
    Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate.

    Subcellular Location:
    Cell membrane; Multi-pass membrane protein.

    Tissue Specificity:
    Widely expressed in normal and in cancer cells.

    DISEASE:
    Defects in SLC16A1 are the cause of symptomatic deficiency in lactate transport (SDLT) [MIM:245340]; also known as erythrocyte lactate transporter defect. Deficiency of lactate transporter may result in an acidic intracellular environment created by muscle activity with consequent degeneration of muscle and release of myoglobin and creatine kinase. This defect might compromise extreme performance in otherwise healthy individuals. 
    Defects in SLC16A1 are the cause of familial hyperinsulinemic hypoglycemia type 7 (HHF7) [MIM:610021]; also known as exercise-induced hyperinsulinemic hypoglycemia. HHF7 is a dominantly inherited hypoglycemic disorder characterized by inappropriate insulin secretion during anaerobic exercise or on pyruvate load.

    Similarity:
    Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.

    Database links:

    Entrez Gene: 6566 Human

    Entrez Gene: 20501 Mouse

    Omim: 600682 Human

    SwissProt: P53985 Human

    SwissProt: P53986 Mouse

    Unigene: 75231 Human

    Unigene: 9086 Mouse



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

    单羧酸转运蛋白家族是哺乳动物细胞膜上一类重要的跨膜转运蛋白,负责乳酸、短链脂肪酸等单羧酸类化合物的跨膜转运,有促进营养物质吸收、代谢动态的平衡、调节胞内pH值以及参与药物输送等多种生物学功能。

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