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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃.
- 保质期:
Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
- 英文名:
Recombinant Mouse Protein jagged-1 (Jag1), partial
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 规格:
20μg
英文名称:
Recombinant Mouse Protein jagged-1 (Jag1), partial品名简称:
Recombinant Mouse Jag1 protein, partial货号:
CSB-EP870758MO规格:
20μg价格:
1836LC-MS/Western Blot:
/SDS-PAGE:
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.纯度:
Greater than 90% as determined by SDS-PAGE.内毒素:
Not test生物活性:
/基因名:
Jag1Uniprot No.:
Q9QXX0别名:
CD_antigen: CD339种属:
Mus musculus (Mouse)蛋白长度:
Partial来源:
E.coli分子量:
53.6 kDa表达区域:
33-334aa氨基酸序列:
GQFELEILSMQNVNGELQNGNCCGGVRNPGDRKCTRDECDTYFKVCLKEYQSRVTAGGPCSFGSGSTPVIGGNTFNLKASRGNDRNRIVLPFSFAWPRSYTLLVEAWDSSNDTIQPDSIIEKASHSGMINPSRQWQTLKQNTGIAHFEYQIRVTCDDHYYGFGCNKFCRPRDDFFGHYACDQNGNKTCMEGWMGPDCNKAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGTCNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNRGTCSNTGPDKYQCSCPEGYSGPNCE蛋白标签:
N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged产品提供形式:
Liquid or Lyophilized powder缓冲液:
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.储存条件:
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.保质期:
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.货期:
3-7 business days注意事项:
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.功能1:
Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. May regulate fibroblast growth factor-induced angiogenesis.功能2:
Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation (By similarity). May regulate fibroblast growth factor-induced angiogenesis.文献:
"The expression of Jagged1 in the developing mammalian heart correlates with cardiovascular disease in Alagille syndrome." Loomes K.M., Underkoffler L.A., Morabito J., Gottlieb S., Piccoli D.A., Spinner N.B., Baldwin H.S., Oakey R.J. Hum. Mol. Genet. 8:2443-2449(1999)研究领域:
Cardiovascular请点击“在线询价”找客服索取产品说明书及引用文献目录,产品实时更新参数、价格信息、更多文献信息可以查看cusabio官网
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文献和实验特定的 CAF-Epi 生态位。该生态位的功能包括:直接驱动肿瘤细胞的增殖与侵袭;通过重塑细胞外基质(ECM)构建物理屏障,阻碍免疫细胞浸润;主动募集并极化 SPP1+巨噬细胞及 CD4+调节性 T 细胞,形成免疫抑制网络,削弱免疫系统对肿瘤的监控与攻击能力。体外共培养及小鼠基因敲除模型验证显示,侵袭性上皮细胞通过 JAG1-NOTCH1 信号通路上调 CXCL1/CXCL8 的表达,进而诱导邻近 NFs 转化为 CAFs 并形成 CAF-Epi 生态位,而敲除 CXCL1/CXCL8 可阻断这一效应
MHC I STREPTAMERS® 检测与分离抗原特异性 (CD8+ T) 细胞
效果对比。染色使用 CMV 阳性个体在 4℃ 下进行。 -染色试剂可逆:染色小鼠抗原特异性 (CD8 + T) 细胞后,再去掉染色。 使用H2 -Kd/LLO91 - 99 Streptamers®染色Listeria monocytogenes, epitope LLO91 - 99 CD8+ T 细胞。用与 LLO91 - 99 特异的 MHC I-Strep H2 -Kd 偶联 Strep-Tactin®PE 观察抗原特异性细胞。 加入 1 mM d-biotin,在不同的时间点监测单体
三句话读懂一篇 CNS:复旦大学研究表明,种花、种草有助预防多种疾病;打呼噜可能增加老年痴呆的风险
医院等多单位合作、裴正康(Ching-Hon Pui)院士作为通讯作者在 Journal of Clinical Oncology 杂志发表研究论文 Coadministration of CD19- and CD22-Directed Chimeric Antigen Receptor T-Cell Therapy in Childhood B-Cell Acute LymphoblasticLeukemia: A Single-Arm, Multicenter, Phase II Trial
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