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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃.
- 保质期:
Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
- 英文名:
Recombinant Human Tumor necrosis factor receptor superfamily member 11A protein (TNFRSF11A), partial (Active)
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 规格:
100μg
英文名称:
Recombinant Human Tumor necrosis factor receptor superfamily member 11A protein (TNFRSF11A), partial (Active)品名简称:
Recombinant Human TNFRSF11A protein, partial (Active)货号:
CSB-AP002321HU规格:
100μg价格:
2568LC-MS/Western Blot:
/SDS-PAGE:
/纯度:
>98% as determined by SDS-PAGE.内毒素:
Less than 1.0 EU/μg as determined by LAL method.生物活性:
Fully biologically active when compared to standard. The ED50 as determined by its ability to inhibit sRANK Ligand induced nuclear factor kappa B(NFkappaB) in RAW 264.7 cells is less than 50 ng/ml, corresponding to a specific activity of > 2.0 × 104 IU/mg in the presence of 15 ng/ml of recombinant sRANK Ligand.基因名:
TNFRSF11AUniprot No.:
Q9Y6Q6别名:
Osteoclast differentiation factor receptor, Receptor activator of NF-KB, CD antigen CD265种属:
Homo sapiens (Human)蛋白长度:
Partial来源:
E.Coli分子量:
19.1 kDa表达区域:
29-202aa氨基酸序列:
QIAPPCTSEKHYEHLGRCCNKCEPGKYMSSKCTTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKALVAVVAGNSTTPRRCACTAGYHWSQDCECCRRNTECAPGLGAQHPLQLNKDTVCKPCLAGYFSDAFSSTDKCRPWTNCTFLGKRVEHHGTEKSDAVCSSSLPARK蛋白标签:
Tag-Free产品提供形式:
Lyophilized powder缓冲液:
Lyophilized from a 0.2 µm filtered 20 mM Tris-HCl, pH 8.0, 150mM NaCl储存条件:
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.保质期:
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.货期:
5-10 business days注意事项:
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.功能1:
Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis. Involved in the regulation of interactions between T-cells and dendritic cells. {ECO:0000269|PubMed:9878548}.功能2:
Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis. Involved in the regulation of interactions between T-cells and dendritic cells.文献:
/研究领域:
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文献和实验Transmembrane Signaling by Receptor Oligomerization
-effector domain (1 ,2 ). The cytoplasmic- effector domain may have enzymatic activity, as is the case for the growth-factor receptor tyrosine kinases (1 ); or it may require interaction with other cytoplasmic-signaling molecules—notably the Janus (JAK
Overview of Receptor Allosterism
Image Figure 1.21.16 Potential error in the pharmacological estimation of the cooperativity factor from a functional receptor assay. The figure
Role of Receptor Tyrosine Kinases in Lung Cancer
Lung cancer cells express receptor tyrosine kinases (RTKs) that may be important targets for therapies. RTKs are proto-oncogenes, which are key regulators for cell growth, differentiation, survival, or motility. More than 50 RTKs
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