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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃.
- 保质期:
Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
- 英文名:
Recombinant Human Interleukin-31 protein (IL31) (Active)
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 规格:
10μg
英文名称:
Recombinant Human Interleukin-31 protein (IL31) (Active)品名简称:
Recombinant Human IL31 protein (Active)货号:
CSB-AP001901HU规格:
10μg价格:
2124LC-MS/Western Blot:
/SDS-PAGE:
/纯度:
>97% as determined by SDS-PAGE.内毒素:
Less than 1.0 EU/μg as determined by LAL method.生物活性:
Fully biologically active when compared to standard. The specific activity is determined by inducing STAT3 activation using human U-87 MG cells. 5 ng/mL of rHuIL-31 can effectively induce STAT3 activation.基因名:
IL31Uniprot No.:
Q6EBC2别名:
IL-31,种属:
Homo sapiens (Human)蛋白长度:
Full Length of Mature Protein来源:
E.Coli分子量:
15.8 kDa表达区域:
24-164aa氨基酸序列:
SHTLPVRLLRPSDDVQKIVEELQSLSKMLLKDVEEEKGVLVSQNYTLPCLSPDAQPPNNIHSPAIRAYLKTIRQLDNKSVIDEIIEHLDKLIFQDAPETNISVPTDTHECKRFILTISQQFSECMDLALKSLTSGAQQATT蛋白标签:
Tag-Free产品提供形式:
Lyophilized powder缓冲液:
Lyophilized from a 0.2 µm filtered PBS, pH7.4储存条件:
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.保质期:
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.货期:
5-10 business days注意事项:
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.功能1:
Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. IL31 may function in skin immunity. {ECO:0000269|PubMed:15184896}.功能2:
Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR文献:
/研究领域:
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文献和实验Immunity | 伤口愈合时为什么会痒?陈万军团队发现竟然和这个免疫细胞有关!
RNA 测序,作者筛选得到 IL-31 作为皮肤切口后诱发瘙痒的候选因子。qPCR 和 ELISA 检测显示 IL-31 表达在创面愈合过程中升高,并在切口后第 5 天达到高峰。在敲除了小鼠 IL-31 后,小鼠在皮肤愈合过程中搔抓的行为明显减少,表明 IL-31 是导致伤口愈合过程中的瘙痒反应的主要因素。图片来源:Immunity那么,IL-31 是如何引起瘙痒的呢?作者发现在切口后 5 天支配伤口部位的背根神经节感觉神经元在愈合过程中 Il31ra(IL-31 受体)、Trpv1(辣椒素受体
,以前曾以淋巴细胞活化因子( lymphocyte activating factor)。细胞促进蛋白质( mitogenic protein)以及 B细胞活化因子( B cell- activating factor)等七种名称称之。而 IL2属于淋巴细胞活素,以前曾以胸腺细胞刺激因子( thymocyte stimulating factor)、 T细胞生长因子( T cell growth factor)等六种名称称之。
troponin蛋白纯化 Protein purification: troponins
Overview TROPONINS The calcium-dependent regulatory protein complex located on the thin actin filaments of muscle comprises of TnC (17.8 kDa), TnI (20.8 kDa), and TnT (30.5 kDa). These proteins are involved in the key
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