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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
- 保质期:
Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
- 英文名:
Recombinant Mouse Interleukin-13 protein (Il13), partial (Active)
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 规格:
500μg/100μg/10μg
| 规格: | 500μg | 产品价格: | ¥27216.0 |
|---|---|---|---|
| 规格: | 100μg | 产品价格: | ¥12132.0 |
| 规格: | 10μg | 产品价格: | ¥2124.0 |
纯度:
>97% as determined by SDS-PAGE.基因名:
Il13,Il-13Uniprot No.:
P20109别名:
IL-13,种属:
Mus musculus (Mouse)蛋白长度:
Partial来源:
E.Coli分子量:
12.3 kDa表达区域:
M+22-131aa氨基酸序列:
M+PVPRSVSLPLTLKELIEELSNITQDQTPLCNGSMVWSVDLAAGGFCVALDSLTNISNCNAIYRTQRILHGLCNRKAPTTVSSLPDTKIEVAHFITKLLSYTKQLFRHGPF蛋白标签:
Tag-Free产品提供形式:
Lyophilized powder缓冲液:
Lyophilized from a 0.2 µm filtered PBS, pH 7.4货期:
5-10 business days注意事项:
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.功能:
Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses (By similarity). {ECO:0000250}.内毒素:
Less than 1.0 EU/µg as determined by LAL method.SDS-PAGE:
/LC-MS Image Description/Western Blot:
/Product types:
Active Protein & In Stock ProteinBiological_Activity:
Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 4 ng/ml, corresponding to a specific activity of > 2.5 × 105 IU/mg.Research Areas:
ImmunologyReconstitution:
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.Reference:
/Function:
Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses (By similarity). Positively regulates IL31RA expression in macrophages风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验开辟先河!STM 背靠背报道非特异性靶点组合 CAR-T 疗法,抗癌效果更好,也更持久
CAR-T 细胞只针对神经系统中的癌细胞。 图片来源:Science Translational Medicine 通过整合来自多个抗原和多个细胞的信息,这些回路本质上提高了精细识别肿瘤这一复杂组织的能力,从而可以更安全、更精确地识别和攻击肿瘤。实验结果表明,EGFRvIII-synNotch -a-EphA2/IL13Ra2 CAR-T 细胞能够有效和完全清除 GBM6 肿瘤,而不会杀死周围的正常组织或体内其他缺少共定位引物抗原的 EphA2 - 或 IL13Ra2 阳性细胞。 图片来源
【讨论】Innate immunity: 'Natural helper' cells identified
lineage (LIN) markers but express interleukin-7 receptor-α (IL-7Rα) and ST2 (a subunit of IL-33R), along with several other cell surface molecules. Further analysis showed that these cells are of lymphoid lineage but are distinct from B and T cells
Th17 Polarization of Mouse CD4 Cells
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