Product overview Description Anti-VCAM1 rabbit polyclonal antibody Applications ELISA, IHC Immunogen Fusion protein of human VCAM1 Reactivity Human, Mouse, Rat Content 0.6 mg/ml Host species Rabbit Ig class Immunogen-specific rabbit IgG Purification Antigen affinity purification
Target information Symbol VCAM1 Full name vascular cell adhesion molecule 1 Synonyms CD106; INCAM-100 Swissprot P19320
Target Background This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene.
Applications Immunohistochemistry Predicted cell location: Cytoplasm and Cell membrane Positive control: Human prostate cancer Recommended dilution: 25-100 Predicted cell location: Cytoplasm and Cell membrane Positive control: Human esophagus cancer Recommended dilution: 25-100
The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using ml223530(VCAM1 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ml223530(VCAM1 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)