- 询价
- gelatins
- JLC260406
- 上海
- 2025年07月11日
- Rabbit
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
江西江蓝纯生物试剂有限公司
- 库存：
大量
- 克隆性：
多克隆
- 保质期：
1年
- 抗体英文名：
Anti-CLDN7 antibody
- 宿主：
Rabbit
- 浓度：
0.3 mg/ml
- 保存条件：
-20°C
- 规格：
25 μl/100 μl/200 μl
Cat. No. JLC260406
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-CLDN7 rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Synthetic peptide of human CLDN7
Reactivity Human, Mouse, Rat
Content 0.3 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol CLDN7
Full name claudin 7
Synonyms CLDN-7, CEPTRL2, CPETRL2, Hs.84359, claudin-1
Swissprot O95471
Target Background
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found.
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm, Cell membrane
Positive control: Human colon cancer
Recommended dilution: 50-150 Predicted cell location: Cytoplasm, Cell membrane
Positive control: Human stomach cancer
Recommended dilution: 50-150
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using ml260406(CLDN7 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human stomach cancer tissue using ml260406(CLDN7 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
Western blotting
Predicted band size:23 kDa
Positive control:Human liver cancer tissue
Recommended dilution: 1000-3000
Gel: 10%SDS-PAGE
Lysate: 30 μg
Lane: Human liver cancer tissue
Primary antibody: ml260406(CLDN7 Antibody) at dilution 1/1050
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution
Exposure time: 40 seconds
ELISA
Recommended dilution: 1000-10000
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