Product overview Description Anti-VCAM1 rabbit polyclonal antibody Applications ELISA, IHC Immunogen Fusion protein of human VCAM1 Reactivity Human, Mouse, Rat Content 0.6 mg/ml Host species Rabbit Ig class Immunogen-specific rabbit IgG Purification Antigen affinity purification
Target information Symbol VCAM1 Full name vascular cell adhesion molecule 1 Synonyms CD106; INCAM-100 Swissprot P19320
Target Background This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene.