Product overview Description Anti-FOSB rabbit polyclonal antibody Applications ELISA, IHC Immunogen Synthetic peptide of human FOSB Reactivity Human, Mouse Content 0.3 mg/ml Host species Rabbit Ig class Immunogen-specific rabbit IgG Purification Antigen affinity purification
Target information Symbol FOSB Full name FBJ murine osteosarcoma viral oncogene homolog B Synonyms AP-1; G0S3; GOS3; GOSB Swissprot P53539
Target Background The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.