PSMD14抗体PSMD14兔多抗抗体Testis tiss
ue sperm binding protein Li 69n antibody抗体PSMD14 Antibody, HRP conjugated抗体- ￥880 - 1320
- CUSABIO
- CN
- CSB-PA018904OB01HU
- 2025年07月11日
- ELISA
- Rabbit
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Peptide sequence from Human 26S proteasome non-ATPase regulatory subunit 14 protein (264-283AA)
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性：
Polyclonal
- 标记物：
HRP
- 适应物种：
Human
- 保质期：
6个月
- 抗原来源：
Homo sapiens (Human)
- 目录编号：
O00487
- 级别：
优
- 库存：
200
- 供应商：
武汉华美生物工程有限公司
- 宿主：
Rabbit
- 应用范围：
ELISA
- 浓度：
>95%,Antigen Affinity Purified
- 靶点：
PSMD14
- 抗体英文名：
PSMD14 Antibody, HRP conjugated
- 抗体名：
Testis tissue sperm binding protein Li 69n antibody
- 规格：
100μl/50μl
| 规格： | 100μl | 产品价格： | ￥1320.0 |
|---|---|---|---|
| 规格： | 50μl | 产品价格： | ￥880.0 |
保存缓冲液
Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
功能
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. The PSMD14 subunit is a metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains within the complex. Plays a role in response to double-strand breaks (DSBs): acts as a regulator of non-homologous end joining (NHEJ) by cleaving 'Lys-63'-linked polyubiquitin, thereby promoting retention of JMJD2A/KDM4A on chromatin and restricting TP53BP1 accumulation. Also involved in homologous recombination repair by promoting RAD51 loading.风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验ChIP‐chip for Genome‐Wide Analysis of Protein Binding in Mammalian Cells
Analysis of Protein‐DNA Binding Sites Basic Protocol 2: Analysis of PCR Array Data Support Protocol 1: Preparation of Annealed Linkers Reagents and Solutions Commentary
：分别是竞争性蛋白质结合分析法[3]、放射性免疫分析法[4]和薄层色谱法[5]。在80年代，放射性免疫分析法得到了广泛的应用和改进，由于这种方法采用放射性核素标记，应用范围受到一定限制，为了进一步提高检测的灵敏度和操作的安全性，进入90年代又陆续发明了各种酶标记法和化学发光法的竞争性ELISA检测试剂盒，这一类检测方法的根本原理都是基于抗体抗原的免疫反应，所有这些试剂盒中采用的抗体全部是兔抗血清或者是经过特异亲和提纯之后的抗cAMP或cGMP的兔多抗，毫无疑问，兔多抗在约四十年的cAMP，cGMP定量
Overview of Protein Microarrays
. Relevant areas of research include the detection of various binding properties of proteins, the study of protein post?translational modifications, the analysis of host?microbe interactions, profiling antibody specificity, and the identification
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