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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Recombinant Human Antigen peptide transporter 2 protein (473-615AA)
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性:
Polyclonal
- 标记物:
Biotin
- 适应物种:
Human
- 保质期:
6个月
- 抗原来源:
Homo sapiens (Human)
- 目录编号:
Q03519
- 级别:
优
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 宿主:
Rabbit
- 应用范围:
ELISA
- 浓度:
>95%,Protein G purified
- 靶点:
TAP2
- 抗体英文名:
TAP2 Antibody, Biotin conjugated
- 抗体名:
sub family B (MDR/TAP) antibody
- 规格:
100μg/50μg
| 规格: | 100μg | 产品价格: | ¥1320.0 |
|---|---|---|---|
| 规格: | 50μg | 产品价格: | ¥880.0 |
保存缓冲液
Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
功能
Involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules. Also acts as a molecular scaffold for the final stage of MHC class I folding, namely the binding of peptide. Nascent MHC class I molecules associate with TAP via tapasin. Inhibited by the covalent attachment of herpes simplex virus ICP47 protein, which blocks the peptide-binding site of TAP. Inhibited by human cytomegalovirus US6 glycoprotein, which binds to the lumenal side of the TAP complex and inhibits peptide translocation by specifically blocking ATP-binding to TAP1 and prevents the conformational rearrangement of TAP induced by peptide binding. Inhibited by human adenovirus E3-19K glycoprotein, which binds the TAP complex and acts as a tapasin inhibitor, preventing MHC class I/TAP association.风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验secondary antibody review -- data from 99 publications
whether any cell surface DFz2 had been internalized 4 flow cytometry localize of GPR30 in the endoplasmic reticulum 5 rhodamine immunocytochemistry detect kaposin B in SLK endothelial cells 6 IgG IgG2b Alexa Fluor 647 flow
祝贺〖雅裕睿安〗成为Signalway Antibody(SAB)独家
SAB(Signalway antibody ) 是一家汇聚了多名专家和学者的新型高科技生物公司,其研发和生产的抗体包括了数百种磷酸化 / 非磷酸化抗体 ( 可以提供同一位点的磷酸化 / 非磷酸化的成对抗体 ) ,为神经科学、细胞信号转导 (Akt pathway , Jat/Sat pathway , MAPK pathway , NF-Kappa B pathway 等 ) 、癌症 / 凋亡、细胞周期、染色质 / 转录、细胞骨架通道、胰岛素 / 葡萄糖、核受体 / 膜受体
:分别是竞争性蛋白质结合分析法[3]、放射性免疫分析法[4]和薄层色谱法[5]。在80年代,放射性免疫分析法得到了广泛的应用和改进,由于这种方法采用放射性核素标记,应用范围受到一定限制,为了进一步提高检测的灵敏度和操作的安全性,进入90年代又陆续发明了各种酶标记法和化学发光法的竞争性ELISA检测试剂盒,这一类检测方法的根本原理都是基于抗体抗原的免疫反应,所有这些试剂盒中采用的抗体全部是兔抗血清或者是经过特异亲和提纯之后的抗cAMP或cGMP的兔多抗,毫无疑问,兔多抗在约四十年的cAMP,cGMP定量
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