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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Peptide sequence around site of Mono-methyl-Lys (36) derived from Human Histone H3.1
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性:
Polyclonal
- 标记物:
Non-conjugated
- 适应物种:
Human
- 保质期:
6个月
- 抗原来源:
Homo sapiens (Human)
- 目录编号:
P68431
- 级别:
优
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 宿主:
Rabbit
- 应用范围:
ELISA, WB, ICC, IF; Recommended dilution: WB:1:500-1:2000, ICC:1:20-1:200, IF:1:50-1:200
- 浓度:
>95%,Antigen Affinity Purified
- 靶点:
HIST1H3A
- 抗体英文名:
Mono-methyl-HIST1H3A (K36) Antibody
- 抗体名:
Histone H3/l antibody
- 规格:
100μl/50μl/20μl
| 规格: | 100μl | 产品价格: | ¥2420.0 |
|---|---|---|---|
| 规格: | 50μl | 产品价格: | ¥1320.0 |
| 规格: | 20μl | 产品价格: | ¥660.0 |
保存缓冲液
Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
功能
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验三句话读懂一篇 CNS,酗酒背后的机制,环境-基因互作诱导肿瘤发生,Cas9 时钟...
大学、阿卜杜拉国王科技大学以及澳门大学的研究人员联合在 Nature 杂志发表论文 Elevated NSD3 histone methylation activity drives squamous cell lung cancer,研究揭示 组蛋白 H3 赖氨酸 36(H3K36) 甲基转移酶 NSD3(其基因位于 8p11-12 扩增子中) 是肺鳞癌(LUSC)肿瘤发生的关键调控因子。体外、体内实验及结构动力学实验表明 H3K36(H3K36me2)的二甲基化显示出增加的催化活性,即 NSD3(T
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