- 询价
- gelatins
- JLC222520
- 上海
- 2025年07月12日
- Rabbit
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
江西江蓝纯生物试剂有限公司
- 库存：
大量
- 克隆性：
多克隆
- 保质期：
1年
- 抗体英文名：
Anti-HYAL2 antibody
- 宿主：
Rabbit
- 浓度：
0.3 mg/ml
- 保存条件：
-20°C
- 规格：
25 μl/100 μl/200 μl
Cat. No. JLC222520
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-HYAL2 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human HYAL2
Reactivity Human, Mouse, Rat
Content 0.3 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol HYAL2
Full name hyaluronoglucosaminidase 2
Synonyms LUCA2
Swissprot Q12891
Target Background
This gene encodes a weak acid-active hyaluronidase. The encoded protein is similar in structure to other more active hyaluronidases. Hyaluronidases degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan and fragments of hyaluronan are thought to be involved in cell proliferation, migration and differentiation. Although it was previously thought to be a lysosomal hyaluronidase that is active at a pH below 4, the encoded protein is likely a GPI-anchored cell surface protein. This hyaluronidase serves as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5' UTR.
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human renal cancer
Recommended dilution: 50-200 Predicted cell location: Cytoplasm
Positive control: Human ovarian cancer
Recommended dilution: 50-200
The image on the left is immunohistochemistry of paraffin-embedded Human renal cancer tissue using ml222520(HYAL2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using ml222520(HYAL2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
ELISA
Recommended dilution: 2000-5000
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