- 询价
- 晶抗生物
- JK260008
- 上海
- 2025年07月14日
- 科研试验
- Rabbit
- Human,Mouse,Rat,Chicken,Dog,Cow,Rabbit,Sheep
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- 详细信息
- 技术资料
- 供应商：
上海晶抗生物工程有限公司
- 库存：
大量
- 克隆性：
多克隆
- 保质期：
1年
- 抗体英文名：
Anti-APAF1 antibody
- 宿主：
Rabbit
- 适应物种：
Human,Mouse,Rat,Chicken,Dog,Cow,Rabbit,Sheep
- 应用范围：
科研试验
- 保存条件：
-20°C
- 规格：
25 μl/100 μl/200 μl
Anti-APAF1 antibody
Cat. No. JK260008
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-APAF1 rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Synthetic peptide of human APAF1
Reactivity Human, Mouse, Rat
Content 0.5 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol APAF1
Full name Apoptotic protease-activating factor 1
Synonyms CED4
Swissprot O14727
Target Background
This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms.
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Anti-APAF1 antibody
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