- 询价
- gelatins
- JLC222009
- 上海
- 2025年07月15日
- Rabbit
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
江西江蓝纯生物试剂有限公司
- 库存：
大量
- 克隆性：
多克隆
- 保质期：
1年
- 抗体英文名：
Anti-CABLES1 antibody
- 宿主：
Rabbit
- 浓度：
0.4 mg/ml
- 保存条件：
-20°C
- 规格：
25 μl/100 μl/200 μl
Cat. No. JLC222009
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-CABLES1 rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Fusion protein of human CABLES1
Reactivity Human, Mouse
Content 0.4 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol CABLES1
Full name Cdk5 and Abl enzyme substrate 1
Synonyms CABL1; IK3-1; CABLES; HsT2563
Swissprot Q8TDN4
Target Background
This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene.
Applications
Immunohistochemistry
Predicted cell location: Nucleus and Cytoplasm
Positive control: Human prostate cancer
Recommended dilution: 25-100 Predicted cell location: Nucleus and Cytoplasm
Positive control: Human esophagus cancer
Recommended dilution: 25-100
The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using ml222009(CABLES1 Antibody) at dilution 1/15, on the right is treated with fusion protein. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ml222009(CABLES1 Antibody) at dilution 1/15, on the right is treated with fusion protein. (Original magnification: ×200)
Western blotting
Predicted band size:68 kDa
Positive control:Mouse brain and heart tissue, mouse liver tissue
Recommended dilution: 500-2000
Gel: 6%SDS-PAGE
Lysate: 40 μg
Lane 1-3: Mouse brain tissue, Mouse heart tissue, mouse liver tissue
Primary antibody: ml222009(CABLES1 Antibody) at dilution 1/350
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution
Exposure time: 1 minute
ELISA
Recommended dilution: 2000-5000
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