Product overview Description Anti-ORC4 rabbit polyclonal antibody Applications ELISA, WB, IHC Immunogen Fusion protein of human ORC4 Reactivity Human, Mouse, Rat Content 1.44 mg/ml Host species Rabbit Ig class Immunogen-specific rabbit IgG Purification Antigen affinity purification
Target information Symbol ORC4 Full name origin recognition complex subunit 4 Synonyms ORC4L; ORC4P Swissprot O43929
Target Background The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. This gene encodes a subunit of the ORC complex. Several alternatively spliced transcript variants, some of which encode the same protein, have been reported for this gene.