Product overview Description Anti-TLR6 rabbit polyclonal antibody Applications ELISA, IHC Immunogen Fusion protein of human TLR6 Reactivity Human Content 0.2 mg/ml Host species Rabbit Ig class Immunogen-specific rabbit IgG Purification Antigen affinity purification
Target information Symbol TLR6 Full name toll-like receptor 6 Synonyms CD286 Swissprot Q9Y2C9
Target Background The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor functionally interacts with toll-like receptor 2 to mediate cellular response to bacterial lipoproteins.
Applications Immunohistochemistry Predicted cell location: Cytoplasm Positive control: Human breast cancer Recommended dilution: 25-100 Predicted cell location: Cytoplasm Positive control: Human thyroid cancer Recommended dilution: 25-100
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using ml221755(TLR6 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using ml221755(TLR6 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)