- 询价
- gelatins
- JLC221139
- 上海
- 2025年07月08日
- Rabbit
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- 详细信息
- 技术资料
- 供应商：
江西江蓝纯生物试剂有限公司
- 库存：
大量
- 克隆性：
多克隆
- 保质期：
1年
- 抗体英文名：
Anti-PLAU antibody
- 宿主：
Rabbit
- 浓度：
0.1 mg/ml
- 保存条件：
-20°C
- 规格：
25 μl/100 μl/200 μl
Anti-PLAU antibody
Cat. No. JLC221139
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-PLAU rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human PLAU
Reactivity Human
Content 0.1 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol PLAU
Full name plasminogen activator, urokinase
Synonyms ATF; QPD; UPA; URK; u-PA; BDPLT5
Swissprot P00749
Target Background
This gene encodes a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in this gene may be associated with late-onset Alzheimer's disease and also with decreased affinity for fibrin-binding. This protein converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen. Plasmin in turn cleaves this protein at a Lys-Ile bond to form a two-chain derivative in which a single disulfide bond connects the amino-terminal A-chain to the catalytically active, carboxy-terminal B-chain. This two-chain derivative is also called HMW-uPA (high molecular weight uPA). HMW-uPA can be further processed into LMW-uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino-terminal fragment. LMW-uPA is proteolytically active but does not bind to the uPA receptor. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human gastric cancer
Recommended dilution: 10-50 Predicted cell location: Cytoplasm
Positive control: Human brain
Recommended dilution: 10-50
The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using ml221139(PLAU Antibody) at dilution 1/10, on the right is treated with fusion protein. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using ml221139(PLAU Antibody) at dilution 1/10, on the right is treated with fusion protein. (Original magnification: ×200)
ELISA
Recommended dilution: 1000-2000
Cat. No. JLC221139
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-PLAU rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human PLAU
Reactivity Human
Content 0.1 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol PLAU
Full name plasminogen activator, urokinase
Synonyms ATF; QPD; UPA; URK; u-PA; BDPLT5
Swissprot P00749
Target Background
This gene encodes a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in this gene may be associated with late-onset Alzheimer's disease and also with decreased affinity for fibrin-binding. This protein converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen. Plasmin in turn cleaves this protein at a Lys-Ile bond to form a two-chain derivative in which a single disulfide bond connects the amino-terminal A-chain to the catalytically active, carboxy-terminal B-chain. This two-chain derivative is also called HMW-uPA (high molecular weight uPA). HMW-uPA can be further processed into LMW-uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino-terminal fragment. LMW-uPA is proteolytically active but does not bind to the uPA receptor. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human gastric cancer
Recommended dilution: 10-50 Predicted cell location: Cytoplasm
Positive control: Human brain
Recommended dilution: 10-50
The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using ml221139(PLAU Antibody) at dilution 1/10, on the right is treated with fusion protein. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using ml221139(PLAU Antibody) at dilution 1/10, on the right is treated with fusion protein. (Original magnification: ×200)
ELISA
Recommended dilution: 1000-2000
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Anti-PLAU antibody
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