Product overview Description Anti-SRGN rabbit polyclonal antibody Applications ELISA, IHC Immunogen Fusion protein of human SRGN Reactivity Human Content 0.3 mg/ml Host species Rabbit Ig class Immunogen-specific rabbit IgG Purification Antigen affinity purification
Target information Symbol SRGN Full name serglycin Synonyms PPG; PRG; PRG1 Swissprot P10124
Target Background This gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis.