Anti-MSR1 antibody

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Anti-MSR1 antibody

Cat. No.     JK222703        
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-MSR1 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Fusion protein of human MSR1
Reactivity                 Human, Mouse
Content                     0.3 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 MSR1
Full name                 macrophage scavenger receptor 1
Synonyms    SRA; SR-A; CD204; phSR1; phSR2; SCARA1
Swissprot    P21757

Target Background
This gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs).