Product overview
Description Anti-IGFBP4 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human IGFBP4
Reactivity Human, Mouse, Rat
Content 0.3 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol IGFBP4
Full name insulin-like growth factor binding protein 4
Synonyms BP-4; IBP4; IGFBP-4; HT29-IGFBP
Swissprot P22692
Target Background
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.