重组人脂肪酸结合蛋白2(FABP2)

特别提示：包括重组人脂肪酸结合蛋白2(FABP2)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人脂肪酸结合蛋白2(FABP2)
英文名称：Recombinant Human Fatty Acid-Binding Protein 2
产品货号：JN1930
产品规格：10μg|50μg|500μg|1mg

本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Asp132在N端、C端都带有His标签。

FABP2质量控制：＞95%(还原性SDS-PAGE)

FABP2制剂：冻干品

FABP2保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

FABP2复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于FABP2：
Fatty Acid-Binding Protein 2 (FABP2) is a cytoplasm protein that belongs to the Fatty-acid binding protein (FABP) family of calycin superfamily. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids. FABP2 is expressed in the small intestine and at much lower levels in the large intestine, the highest expression levels in the jejunum. FABP2 binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis and may also help maintain energy homeostasis by functioning as a lipid sensor.

除了重组人脂肪酸结合蛋白2(FABP2),，我公司还供应以下相关产品：



名称：重组人TDGF1(畸胎瘤衍生生长因子)
货号：JN0248
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物表达系统制备，目的基因编码的Leu31-Ser169在N端含有Fc标签。

TDGF1质量控制：＞95%(还原性SDS-PAGE)。

TDGF1制剂：冻干品

TDGF1保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

TDGF1复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于TDGF1：
Teratocarcinoma-derived growth factor 1(TDGF1) is a Cell membrane protein and contains 1 EGF-like domain. The protein plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects. It also may play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm.

名称：重组人双糖链蛋白多糖(Biglycan)
货号：JN0541
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Glu20-Lys368在C端含有His标签。

Biglycan质量控制：＞95%(还原性SDS-PAGE)

Biglycan制剂：冻干品

Biglycan保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

Biglycan复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于Biglycan：
Biglycan is a 200-350 kD proteoglycan consisting of a 45 kD core protein and two chrondroitin/dermatan sulfate glycosaminoglycan chains. Biglycan binds to TGF-ß. It also binds to collagen type I in low ionic strength (less than 3 mM phosphate) buffer. At higher ionic strengths, Biglycan does not bind to collagen type I. It enhances the inhibition effect of TGF-ß on osteoclast proliferation at a concentration of 4-20 mg/ml. It also prevents the attachment of CHO cells to fibronectin, with a 50% inhibition at 17-21 mg/ml.

名称：重组人NELL1(神经性类EGF蛋白1)
货号：JN0795
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Arg17-Asn810在C端含有His标签。

NELL1质量控制：＞95%(还原性SDS-PAGE)

NELL1制剂：液体

NELL1保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于NELL1：
Protein Kinase C-Binding Protein NELL1 is a member of EGF-like domain containing family. NELL1 is a secreted protein and contains six EGF-like domains, one TSP N-terminal (TSPN) domain and five VWFC domains. NELL1 exists as a homotrimer which may be involved in cell growth regulation and differentiation. It is reported that NELL1 enhances new blood vessel formation (angiogenesis) and controls inflammation, which are critical elements in treating severe radiation dermatitis, skeletal muscle wounds, cardiac tissue damaged by acute myocardial infarction (AMI), or heart attack.

名称：重组人表皮生长因子受体(EGFR)(HER1 mutant)
货号：JN1439
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Leu25-Val30Gly&Asn298-Ser645在C端带有Fc标签。

EGFR/HER1 mutant质量控制：＞95%(还原性SDS-PAGE)

EGFR/HER1 mutant制剂：冻干品

EGFR/HER1 mutant保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

EGFR/HER1 mutant复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于EGFR/HER1 mutant：
The EGFR subfamily of receptor tyrosine kinases is composed of EGFR, ErbB2, ErbB3 and ErbB4. The EGFR shares 43% - 44% aa sequence identity with the ECD of human EGFR subfamily. All these family members are type I transmembrane glycoproteins with an extracellular ligand binding domain. The extracellular ligand binding domain is containing two cysteine-rich domains separated by a spacer region and a cytoplasmic domain containing a membrane-proximal tyrosine kinase domain. Ligand binding could induce EGFR homodimerization and heterodimerization with ErbB2, resulting in cell signaling, heterodimerization tyrosine phosphorylation and kinase activation. It can bind EGF, amphiregulin, TGF-alpha, betacellulin, epiregulin, HB-EGF, epigen, and so on. Its signaling regulates multiple biological functions including cell proliferation, differentiation, motility, and apoptosis. EGFR can also be recruited to form heterodimers with the ligand-activated ErbB3 or ErbB4. EGFR is overexpressed in different tumors. Several anti-cancer drugs use EGFR as target.