2,3,5-Triphenyltetrazolium chloride has been used to stain heart tissue to measure the extent of acute lesion.[2] It has also been used to stain brain tissue to check the size of infarct area.[3]
General description
2,3,5-Triphenyltetrazolium chloride is a colorless water-soluble dye. In the mitochondria of living cells, it is reduced to a deep red, water-insoluble compound (formazan). 2,3,5-Triphenyltetrazolium chloride helps to distinguish between viable and infarcted brain tissue after stroke.[1]