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- 详细信息
- 文献和实验
- 技术资料
- 抗体英文名:
Vimentin
- 供应商:
上海研卉生物科技有限公司
- 库存:
大量
- 保质期:
一年
- 规格:
100ug
Vimentin Protein, Human, Recombinant (His Tag)
1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
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文献和实验Discovery of Lamin B1 and Vimentin as Circulating Biomarkers for Early Hepatocellular Carcinoma
electrophoresis (2DE) and MALDI-TOF/TOF mass spectrometry, our groups have identified lamin B1 (LMNB1) and vimentin (VIM) as promising biomarkers for detection of early HCC. Protein levels of both biomarkers were significantly elevated in cancerous tissues
. Here, we describe the detection of autoAbs to various self-antigens with different tissue restriction patterns which includes collagens, k-α1 tubulin, vimentin, and myosin. We also discuss their relevance in monitoring for rejection following solid organ transplantation.
),已经被证明可以对抗真菌感染,并可能有助于预防癌症和心血管疾病。在癌细胞中,ajoene作用于多个靶点,但很少有特异靶点被发现。在这项研究中,Kaschula等人发现ajoene的目标之一是蛋白vimentin,这是一种结构蛋白,在一些癌症中过表达,有助于增加肿瘤的侵袭性。他们发现,在癌细胞中过量表达vimentin可以促进癌细胞的迁移,但暴露于ajoene则完全阻断了这种作用。作者认为ajoene在特定的半胱氨酸残基上与波形蛋白结合,阻止波形蛋白形成功能丝,从而抑制其亲迁移活性。有趣
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