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- 2025年07月16日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
632
- 英文名：
Recombinant Human Homeobox protein B4
- 保质期：
6个月
- 供应商：
北京百奥莱博科技有限公司
- 保存条件：
收到货后请置于-20℃
特别提示：包括重组人HOXB4(mutant)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
产品名称：重组人HOXB4(mutant)
英文名称：Recombinant Human Homeobox protein B4
产品规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Leu251在N端含有His标签。
HOXB4(mutant)质量控制：＞95%(还原性SDS-PAGE)
HOXB4(mutant)制剂：液体
HOXB4(mutant)保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。
关于HOXB4(mutant)：
Homeobox B4 (HOXB4) is encoded by the HOXB4 gene which is a member of the the class I homeobox (HOX) gene family and encodes a nuclear protein with a homeobox DNA-binding domain. These genes are master control regulators of developmental programs including embryonic and adult hematopoiesis. Multiple HOX genes, including HOXB4, are highly expressed in the hematopoietic stem cells (HSC) comp*(代"a")rtment. HOXB4 gene can act in opposite ways when expressed by different cells, promoting the proliferation of stem cells whilst activating the apoptotic pathway in some embryonic structures. The protein HOXB4, as a homeodomain transcription factor, has been shown to be an important regulator of stem cell renewal and hematopoiesis. Incellular or ectopic expression of HOXB4 expands hematopoietic stem and progenitor cells in vivo and in vitro, making it a potential candidate for therapeutic stem cell expansion.
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